Wednesday, September 02, 2009

Heads-Up

"If this report is confirmed it raises the prospect of the potential evolution by genome subunit reassortment of a highly transmissible influenza virus like the pandemic (H1N1) 2009 virus with the enhanced virulence of the avian (H5N1) virus"


H5N1/H1N1 VIRUS CO-INFECTION - EGYPT: ex SAUDI ARABIA, SUSPECTED

A sample taken from a 28 year-old man who arrived at the port of
Safaga from Saudi Arabia after performing Umrah [pilgrimage] has
tested positive for [both] bird and swine flu [that is, presumably avian
influenza (H5N1) virus and pandemic (H1N1) 2009 virus infections]. He
was immediately detained and held in isolation in a hospital in
Hurghada.

Mohammad Rifai, director-general of preventative medicine, stated that
this case is the 3rd in 2 days. (The other 2 are a 35-year-old Italian
tourist also retained at the hospital in Hurghada and] another
pilgrim, 30 years old, who has been detained in Safaga Central
Hospital. Rifai pointed out that a sample from a 38-year-old citizen has tested negative.

Another 2 cases have been detained in Mansoura fever hospital on
suspicion of similar illness.

5 cases, including 4 children, suspected of having contracted
"bird flu" infection [presumably avian influenza (H5N1) virus
infection] have been detained in Mansoura Chest hospital.

(Byline: Mohamed Soliman)

--
Communicated by:
ProMED-mail

(Does the director-general of preventative medicine mean this case is
the 3rd in 2 days of *dual* infection? Unless both *viruses* were
detected in the patient, not simply positive antibody results, this
would be inconclusive, since Egypt has reported cases of H5N1
throughout 2009, and this person may have had a mild infection before
leaving for Saudi Arabia. Saudi Arabia has reported 285 cases (no
deaths) of H1N1 in 2009 -- see last case count of 22 July in ProMED
ref. below -- but it is also possible that the Egyptian
pilgrim(s) could have caught H1N1 from a pilgrim from another
H1N1-infected country.- Mod.JW)

(If this report is confirmed it raises the prospect of the potential
evolution by genome subunit reassortment of a highly transmissible
influenza virus like the pandemic (H1N1) 2009 virus with the enhanced
virulence of the avian (H5N1) virus. Further information is awaited
confirmatory or not, by laboratory analysis, of the occurrence of dual
infection. - Mod.CP]


http://www.isid.org/

http://www.promedmail.org/pls/otn/f?p=2400:1001:3296779846092559::NO::F2400_P1001_BACK_PAGE,F2400_P1001_PUB_MAIL_ID:1000,79041

4 comments:

CDD13 said...

Allan,

This is an interesting read on the whole Swine Flu pandemic/vaccination/deaths issue

The H1N1 Swine Flu Pandemic: Manipulating the Data to Justify a Worldwide Public Health Emergency.

http://www.globalresearch.ca/index.php?context=va&aid=14901

Anonymous said...

H5N1/H1N1 VIRUS CO-INFECTION - EGYPT (02): ex SAUDI ARABIA, NOT
***************************************************************
A ProMED-mail post

ProMED-mail is a program of the
International Society for Infectious Diseases



Date: Tue 1 Sep 2009
Source: Youm7 [in Arabic, machine trans., edited]
www.youm7.com/News.asp?NewsID=132676

The Ministry of Health through the Council of Ministers daily report
on the situation regarding swine flu [pandemic (H1N1) 2009 influenza
virus infection], has now discounted the rumour of [a co-infection]
with avian influenza virus of one of the cases infected with H1N1 type
virus upon his arrival at the port of Safaga from Umrah [pilgrimage to
Saudi Arabia].

The Ministry said that this pilgrim was infected with swine flu
[pandemic (H1N1) 2009 virus] in addition to a common [seasonal] flu
and not bird flu [avian H5N1 influenza virus]. [Previously it was
suggested that the patient was co-infected with H1N1 and H5N1 viruses.
- Mod.CP]. This patient's health is good and his condition stable. He
will leave hospital within 2 days after treatment. This emphasizes the
lack of any potential interaction between a mutant avian H5N1 virus in
Egypt and an H1N1 strain.
[Byline: Mona Zia]
--
Communicated by:
ProMED-mail Rapporteur Mary Marshall

******
Date: Wed, 2 Sep 2009 11:44:45 -0500 [12:44:45 EDT]
From: Jason Garner jasonlgarner at gmail dot com

I would like to pass on information just released by both PLoS and the
NIH regarding interaction of the pandemic A(H1N1) with co-infections
of seasonal flu viruses.

A University of Maryland/NIH study, using ferret animal models,
suggests that co-infections of A(H1N1) with seasonal flu viruses do
not produce chimeric or reassortant viruses. Said another way, the
A(H1N1) outcompetes seasonal viruses, possibly demonstrating the
pandemic strain is not under biological pressure and is perhaps more
efficiently communicable.

However, with regard to the H5N1-A(H1N1) co-infections reported
recently, there is no data to suggest these latest findings could
apply to H5N1 co-infections. In light of the characteristic that HPAI
H5N1 has been shown to be a "dead-end" infection in humans, it could
possibly be out-competed by a more robust strain such as A(H1N1)
rather than being a player in a recombination event.

Link to the NIH study results summary:
www.nih.gov/news/health/aug2009/niaid-31.htm

--
Jason L Garner
Senior Molecular Biologist
Global Influenza Surveillance

Anonymous said...

Allan, as i look thru any number of avian/swine flu stock baskets and news articles, i never see NNVC listd or mentioned in any of them. It seems to me that the managemnet of NNVC needs to communicate the full range of potential products to the market. More PR. Iknow you talk with ceo occasianally, so tell him to spread the word re: their ability to kill all virus including flu and herpes etc. thanks for the time and effort you put into this site.

P.S. just wait a few days so i can buy a few more thousand shares. LOL
mac

Anonymous said...

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